MSc Yukun Su

Yukun Su

University Medicine Rostock
Department of Orthopaedics

Phone: +49-381-494-9375
Fax: +49-381-494-9308
www: forbiomit.med.uni-rostock.de
Email: yukun.su(at)uni-rostock.de

Topic

Electro-stimulating Implants for Bone Regeneration: Parameter Analysis and Design Optimization

Description

The goal of the project is to analyze relevant parameters of electro-stimulating implants and their respective impact on bone regeneration in order to optimize the implant's design and stimulating parameters. Optimization will be approached through computational simulations. The simulations are supported by experimental measurements in cooperation with correlated projects.

Approach

In essence, this project progresses in the following three stages:

  1. Simulating the electric field on a composite femoral head model with different parameters.
  2. Simulating the electric field and experimental validation using a human femoral head.
  3. Analyses different electric field parameters in an animal model for verification of the numerical simulation
  4. Classifying the available MRI data and stimulating the electric field on the human femoral head model with different bone defects according to the classification from MRI.

Results

So far the following results have been achieved:

  1. Electric field simulation on a composite femoral head model with different parameters.
  2. Electric field simulation on a human femoral head model with different parameters and experimental validation.
  3. Numerical simulation of the electric field distribution in an animal model.
  4. Optimisation of the electro-stimulation implants position with avascular necrosis of the femoral head.
  5. Automatically calibrating dielectric bone properties with iSIGHT and COSMOL

Publications

Reviewed paper important congresses

  • SU, J., SOUFFRANT, R., KLUESS, D., ELLENRIEDER, M., van RIENEN, U., MTTELMEIER, W. and BADER, R., 2013. Dependence of the electric field distribution in the femoral head on position and design of an electro-stimulating implant, Biomedical Engineering / Biome-dizinische Technik, Band 58, Heft SI-1 Track-N (Aug 2013), Proceedings BMT (Biomedizinische Technik) 2013 - Dreilän-dertagung der Deutschen, Schweizerischen und Österreichischen Gesellschaft für Biomedizinische Technik, Graz, Austria, 19-21 Sept. 2013,  (2 pages), DOI 10.1515/bmt-2013-4346.
  • ZHUNG, J., SU, Y., STEUER, R., BADER, R., van Rienen, U. and KOLB, J.K. 2013.  Time Domain Dielectric and Impedance Spectroscopy for Electrically Stimulated Cells and Tissues (1-page abstract), 15th International Conference on Electrical Bio-Impedance (ICEBI 2013), Heilbad Heiligenstadt, Germany, April 22-25, 2013.
  • SU, Y.,  SOUFFRANT, R., KLUESS, D., ELLERIED, M., MITTELMEIER, W., van RIENEN, U. and BADER, R., 2013. Evaluation of Electric Field Distribution in Electromagnetic Stimulation of Human Femoral Head, Bioelectromagnetics, (submitted).
  • SU, Y., SOUFFRANT, R., ELLENRIEDER, M., MITTELMEIER, W. and BADER, R., 2012. Parameter analysis on design and position of an electro-stimulating screw implant used for treatment of avascular necrosis of the femoral head. Abstract Book, 13th EFORT Congress. (Accepted)
  • SU, Y., SOUFFRANT, R., RUTHER, C., KLUESS, D., ELLENRIEDER, M., EWALD, H., MITTELMEIER, W. and BADER, R., 2012. Numerical design analysis of an electro-stimulating implant for bone regeneration therapy of avascular femoral head necrosis. Abstract Book, World Congress Medical Physics and Biomedical Engineering. (Accepted)

Supervisors