Investigation of electro-stimulating implants for bone regeneration and prevention of implant-associated bacterial infection using DC.
Parameter analysis and surface coatings optimization, in-vitro investigation.

The scientific objective of the project is to analyze correlated parameters of DC electro-stimulating implants and their respective impact on bone regeneration and influence on biofilm formation at the implant surface in order to optimize stimulating parameters and implant surface coatings.

The parameters for DC stimulation will be optimized in a finite element analysis (FEA). Numerical simulations are to be supported and validated by experimental measurements for this task.

• Modify of an in-vitro system for electric stimulation using DC
• Simulating the electric field on a test chamber with different parameters
• Simulating the electric field and experimental validation using an in-vitro system
• Verification of electric stimulation effects on bone regeneration and influence on biofilm formation

Publications (2015/2016)
reviewed paper important congresses

• BENDER, T., SASS, M., WOLF, A., MITTELMEIER, W., BADER, R. and KLUESS, D., 2015. Finite element analysis into eigenfrequencies and attenuation of a total hip stem with different levels of loosening. 9. Jahrestagung der Deutschen Gesellschaft für Biomechanik. Bonn, Germany
• BENDER, T., SASS, M., MITTELMEIER, W., BADER, R. and KLUESS, D., 2015. Finite Element Analysis into Eigenfrequencies of a Total Hip Stem with Different Levels of Loosening. COMSOL Conference 2015 Grenoble, France.
• BENDER, T., SASS, M., BADER, R. and KLUESS, D., 2015. SMART-HIP - Entwicklung und Auslegung eines Sensorsystems für die Messung der Verankerung von Implantaten. 12. Dresdner Sensor-Symposium. Dresden, Germany.
• BENDER, T., SASS, M., BADER, R. and KLUESS, D., 2016. Employing Principal Component Analysis And Support Vector Machines To Classify Different Levels Of Loosening Of A Total Hip Stem. ORS (Orthopaedic Research Society) Orlando, USA.
• BENDER, T., SASS, M., BADER, R., KLUESS, D., SPORS, S., 2016. Körperschallanalyse zur Klassifizierung einer Lockerung in Hüftendoprothesen.  42. Jahrestagung für Akustik. Aachen, Germany.

Patente
Eingereicht 25.09.2015:

• BENDER T., BADER R., SASS M., KLUESS D. und SCHULZE C., Ein im Implantat integrierter mechanischer Schwinger zur Erzeugung von Mikrovibrationen für verbesserte Knochenheilung

In addition to the entire graduate school, my supervisors are:

• Prof. Bernd Kreikemeyer
• Prof. Rainer Bader