M.Sc. Simone Krüger

Topic

Investigation of combined electrical and mechanical stimulation on osseous cells

Description

Electro-mechanical stimulation of osseous cells may have a relevant effect on implant integration and on hard tissue regeneration. This project aims to investigate the influence of combined electrical and mechanical stimulation on the proliferation and differentiation on osseous cells.

Approach

  • Development and validation of an in vitro test system for combined electrical and mechanical stimulation
  • Cellular and molecular biologic analysis of combined electrical and mechanical stimulation effects on human osteoblasts and osteoclasts
  • Identification of optimal stimulation parameters

Publications

Peer-reviewed conferences

Jonitz-Heincke A, Krüger S, Schröder M, Hansmann D, Utzschneider S, Kretzer JP, Ziebart J, Bader R: Einfluss von Metallionen und Metallpartikeln aus CoCr28Mo6 auf die Neusynthese der knöchernen Extrazellulärmatrix. Osteologie 2016, Vol 25(1): A41-A42.